Postdoctoral Fellowship - Cancer Detection and Experimental Therapeutics (PF-CDET)

Areas Reviewed

• Biomarker identification and pre-clinical development, including liquid biopsy and molecular imaging
• Pre-clinical modeling to identify factors (such as microbiota, pathogens, nutrition, metabolism, oxygen levels, oncogenes, and tumor suppressor genes) and their mechanisms of action contributing to cancer progression
• Mechanisms of therapeutic response, including tumor evolution and treatment resistance
• Mechanisms of treatment-associated morbidities
• Active and passive immune therapies for cancer, adoptive transfer of autologous or allogeneic hematopoietic cells, and targeted delivery of toxic payloads
• Isolation, testing, and synthesis of natural products
• Modification and development of drugs
• Toxicity and effectiveness of therapeutic agents and drug delivery systems (including nanotechnology and microbial strategies)
• Molecular imaging for pre-clinical therapeutic development
• Pharmacology/pharmacogenetics/pharmacogenomics
• Gene therapies and gene target validation