Research We Fund: Extramural Discovery Science

Biochemistry and Immunology of Cancer

Scientific Director: 
Doug Hurst, PhD

Scientist: 
Santina Snow, PhD

For all questions, contact: 
santina.snow@cancer.org

The Biochemistry and Immunology of Cancer Program focuses on fundamental mechanisms of cancer initiation, progression, and prevention. Emphasis is placed on molecular studies encompassing structure, function, interaction, signaling, and regulatory pathways. The following areas of research are relevant to this program:

  • Genetic and epigenetic regulation of gene expression
  • Mechanisms of DNA damage/repair and genomic instability
  • Functional and structural analysis of macromolecules including DNA, RNA and proteins
  • Protein modification, structure, function, interactions with nucleic acids or proteins and degradation
  • Cellular metabolism and signaling
  • Basic mechanisms of tumor immunology and hematologic malignancies

 

For more information on our grant making process, please visit Our Grant Process.

To view all of our peer review committees, please visit our Peer Review Committees webpage.

Glossary for Nonscientists

Featured Term:
Germline Pathogenic Variations

A type of mutated gene that gets passed down from a parent to child and that causes disease, such as cancer. The BRCA1 and BRCA2 mutations are examples of germline pathogenic variations because they are passed down by parents and increase the risk of developing several types of cancer.