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Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat. We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
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- Triggering Signals of BRCA1 Breast Cancer (K Kessenbrock)
- Testing Diverse Groups Finds New Breast Cancer Genes (L Teras)
- Black Women & Genetic Testing (J Palmer)
- Women 65+ & Genetic Tests for Breast Cancer Risk (L Teras)
- High-Risk Genes and Screening (A Patel)
- New Risk Calculation May Affect Breast Cancer Screening (L Teras)
- Black Men and Breast Cancer (H Sung)
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- AI Tool Improves Breast Cancer Prognosis Accuracy
- Exercise & Sitting Time (E. Rees-Punia)
- Cancer Risk Factors in LGBTQ Populations (B. Charlton)
- CPS-3 Disparities Studies
- Cancer Disparities in the US (F. Islami)
- Housing Assistance and Mammograms (H Lee)
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- Podcasts, TheoryLab
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- Genetic Risks (L Teras)
- New Medulloblastoma Drugs (J Rodriguez-Blanco)
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- Increase in Brain Tumor Diagnosis (K Miller)
- Longer Life Expectancy for Survivors (J Yeh)
- Potential Target for New Osteosarcoma Drugs (C Benavente)
- At-Home Chemo for Children with HR ALL (L Ranney)
- Childhood Cancer Research Landscape Report
- Tumor-Infiltrating Neutrophils (R. Sumagin)
- New Epigenetic Target (K Rai)
- Extra Chromosomes (Aneuploidy) Effect on Cancer (J. Sheltzer)
- Discovery of a New Biomarker Is the First Step to New Treatment (C. Maher)
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- Tiny Sensor in Mice May Find Cancer That's Trying to Spread (L. Hao)
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- Availability of Healthy Food (L Tussing-Humphreys)
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- Fewer than 10K Steps/Day (A Patel)
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- Stage 2 Clinical Trials for New Endometrial Cancer Drug (V Bae-Jump)
- Hard-to-Starve Pancreatic Cancer Cells (N Kalaany)
- Coffee Risks for Colorectal Cancer (C Um)
- Food Parasite & Brain Cancer Risk (J Hodge)
- Exercise & Quality of Life in Older Survivors (E Rees-Punia)
- 21 Metabolites Linked with Breast Cancer (Y Wang)
- Replacing Sitting May Affect Weight (E Rees-Punia)
- CPS-3 Researchers Ask What People Eat and Check Urine Samples (Y Wang)
- Video Games Motivate Exercise? (E. Lyons)
- Food Choices and Colon Cancer Risk (P. Chandler)
- Race, Exercise & Breast Cancer (C. Dallal)
- Diet with Colorectal Cancer (M. Guinter)
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- Kickstart NSCLCs Clinical Trials (L. Eichner)
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- Mouse Lung Organoids for Research (C Kim)
- Quality of Life for Lung Cancer Survivors (J Temel)
- Precision Therapies for NSCLC (P Jänne)
- Cancer Deaths from Smoking (F Islami)
- Lung Cancer Surgery Disparities (A Jemal)
- BRG1-Deficient Lung Cancers (C Kim)
- Yoga for Couples with Lung Cancer (K Milbury)
- Metabolic Differences as New Drug Targets (A Marcus)
- CPS-II & CPS-3 Inform About Risks of Ovarian Cancer
- Machine Learning & Glowing Nanosensors (D Heller)
- Ovarian Cancer May Start in Fallopian Tube Cells (K Lawrenson)
- New Gene Linked with Deadliest Type (C Han)
- Gene-Testing Tools May Personalize Care (A Sood)
- Chromosome-Hoarding Ovarian Cancer Cells & Treatment (J Sheltzer)
- Nanoparticles as Drug Delivery for Metastases (X Lu)
- Turning Off 2 Proteins to Slow HGSC (P Kreeger)
- Targeted Light Therapy in Mice (M Bai)
- Nanoparticles, CAR T, and CRISPR (M Stephan)
- Endometriosis & Ovarian Cancer in Mice (M Wilson)
- Ovarian Cancer Special Section
- UV Exposure, Melanoma, & Dark Skin Types (A. Adamson)
- Melanoma and Lipid Droplets (R. White)
- Zebrafish and Acral Melanoma (R. White)
- T-Cell Lymphoma and PD1 (J. Choi)
- New Drug Destroys Cancer-Causing Protein (C. Crews)
- Virus & Merkel Cell Skin Cancer (R. Wang)
- Non-Genetic Drug Resistance (S. Spencer)
- Hijacking the Body's Sugar (R. Wang)
- Telling about High Risk (P. Kanetsky)
- Brain Metastasis and Alzheimer’s (E. Hernando)
- Exhausted Melanoma "Killer" Cells (W. Cui)
CPS-II & CPS-3 Studies Inform About the Risks of Ovarian Cancer
Data from Cancer Prevention Study-II (CPS-II) and CPS-3 participants reveal key facts about the risks of developing ovarian cancer.
Alpa Patel, PhD, Lauren Teras, PhD, and other American Cancer Society (ACS) epidemiologists have used data collected from participants in our Cancer Prevention Study II (CPS-II) for several published research projects. Here are some of the key findings:
- Those who sit for 6 hours (Leisure-Time Spent Sitting and Site-Specific Cancer Incidence in a Large U.S. Cohort) or more a day during leisure time (not at work) have a higher risk of developing ovarian cancer, and of developing cancer in general, compared with those who sit fewer than 3 hours a day.
- After menopause, the risk of developing ovarian cancer increases 25% for every 5 years of estrogen-only (without progestin) hormone replacement therapy. Women who use estrogen-only hormone replacement therapy for 20 years or more have a nearly 3 times higher risk of developing ovarian cancer.
- Those who have a rotating shift-work schedule have a higher risk of dying from ovarian cancer than those who don’t.
- Moderate to vigorous exercise, specifically walking, does not seem to reduce the risk of ovarian cancer.
We're Testing Participant Blood Samples to Learn More About Biomarkers & Genetic Risks
Thanks to CPS-II and CPS-3 participants, we have blood samples to find biomarkers that will identify early signs of ovarian cancer and to find information about risk factors that are hard to capture through questionnaires, such as how to identify inherited genetic mutations that increase a woman’s risk for ovarian cancer.
ACS investigators are testing the blood samples in collaboration with Ovarian Cancer Cohort Consortium (OC3) investigators.
The ACS’s CPS-II Nutrition Cohort is part of the Collaborative Group on Epidemiological Studies of Ovarian Cancer. This group helped establish the increased risk for ovarian cancer in women with excess body weight and the decreased risk of ovarian cancer for women who use oral contraceptives.”
Alpa Patel, PhD
Senior Vice President Population Science
American Cancer Society
Featured Term: Biomarker
A measurable molecular, genetic, chemical, or physical characteristic in the blood or other bodily fluids, such as sweat and tears, that is a sign of a normal or abnormal process or of a health condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease.
Featured Term: Susceptibility Biomarkers
A biomarker that signals the potential, or risk, a person has to develop a disease before they have symptoms. For instance, low-density lipoprotein (LDL) cholesterol is a susceptibility biomarker for heart disease.